Journal article
Differential regulation of matrix metalloproteinases in human cancer cells by exogenous factors.
Abstract
Matrix degradation by cancer cells is an important attribute of malignant behaviour. We have postulated that during invasion and metastasis, matrix metalloproteinase (MMP) production by cancer cells is modulated by microenvironmental factors. To determine this, we screened human cancer cell lines of diverse histogenesis for their secreted MMP profile following exposure to a diversity of soluble and insoluble agents. Enzymatic changes were …
Authors
Sanchezsweatman O; Soares F; Whaley M; Khokha R; Orr F; Singh G
Journal
International Journal of Oncology, Vol. 11, No. 6, pp. 1321–1326
Publisher
Spandidos Publications
Publication Date
12 1997
DOI
10.3892/ijo.11.6.1321
ISSN
1019-6439