Journal article
Mitochondrial alterations in photodynamic therapy-resistant cells.
Abstract
The characterization of radiation-induced fibrosarcoma cells (RIF-8A) which have been selected for resistance to Photofrin-mediated photodynamic therapy (PDT) is detailed in this report. Morphological and functional assessment of mitochondria in both the resistant RIF-8A and parental RIF-1 cells show distinct differences. Electron micrographs show that the mitochondria in the RIF-8A cells are relatively smaller; stain more densely, and display …
Authors
Sharkey SM; Wilson BC; Moorehead R; Singh G
Journal
Cancer Research, Vol. 53, No. 20, pp. 4994–4999
Publication Date
October 15, 1993
ISSN
0008-5472