Journal article
BDNF-Dependent Effects on Amygdala–Cortical Circuitry and Depression Risk in Children and Youth
Abstract
The brain-derived neurotrophic factor (BDNF) is critical for brain development, and the functional BDNF Val66Met polymorphism is implicated in risk for mood disorders. The objective of this study was to determine how the Val66Met polymorphism influences amygdala-cortical connectivity during neurodevelopment and assess the relevance for mood disorders. Age- and sex-specific effects of the BDNF Val66Met polymorphism on amygdala-cortical …
Authors
Wheeler AL; Felsky D; Viviano JD; Stojanovski S; Ameis SH; Szatmari P; Lerch JP; Chakravarty MM; Voineskos AN
Journal
Cerebral Cortex, Vol. 28, No. 5, pp. 1760–1770
Publisher
Oxford University Press (OUP)
Publication Date
May 1, 2018
DOI
10.1093/cercor/bhx086
ISSN
1047-3211