Journal article
Synthesis and biosynthetic utilization of radioactive photoreactive fatty acids.
Abstract
A synthesis of a homologous series of highly radioactive photoreactive fatty acids has been developed. Oxidative cleavage of the cis double bonds of unsaturated fatty acids by NaIO4/OsO4 produced the omega-oxo fatty acids; subsequent reduction by [3H]NaBH4 afforded a series of highly radioactive [omega-3H]hydroxy fatty acids to which a variety of photoreactive probes can be readily attached. In this study, the m-diazirinophenoxy group was …
Authors
Leblanc P; Capone J; Gerber GE
Journal
Journal of Biological Chemistry, Vol. 257, No. 24, pp. 14586–14589
Publisher
Elsevier
Publication Date
December 1982
DOI
10.1016/s0021-9258(18)33313-1
ISSN
0021-9258