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Characterization of SERCA2b Ca2+–Mg2+ ATPase mRNA...
Journal article

Characterization of SERCA2b Ca2+–Mg2+ ATPase mRNA decay by nuclear proteins

Abstract

Gene expression is controlled at several levels including mRNA decay. Sarco/endoplasmic reticulum Ca2+-Mg2+-ATPase isoform 2b (SERCA2b) is central to Ca2+ signalling and homeostasis in several tissues. SERCA2b mRNA decay involves interactions between cis-acting elements in its 3'-region and trans-acting nuclear protein factors. In the presence of the protein factors, the synthetic capped and polyadenylated RNA fragment 2b1 (3444-3753) decays …

Authors

Chen T; Ghosh P; Misquitta CM; Govindan A; Grover AK

Journal

Cell Calcium, Vol. 41, No. 6, pp. 581–592

Publisher

Elsevier

Publication Date

June 2007

DOI

10.1016/j.ceca.2006.10.008

ISSN

0143-4160