Journal article
Plasma membrane calcium pump activity in rat pancreatic islets
Abstract
The aim of this study was to quantify the glucose modulation of the plasma membrane calcium pump (PMCA) function in rat pancreatic islets. Ca2+-ATPase activity and levels of phosphorylated PMCA intermediates both transiently declined to a minimum in response to stimulation by glucose. Strictly dependent on Ca2+ concentration, this inhibitory effect was fully expressed at physiological concentrations of the cation (less than 0.5 μM), then …
Authors
Rossi JPFC; Villamil AM; Echarte MM; Alzugaray ME; Borelli MI; García ME; Pande J; Grover AK; Gagliardino JJ
Journal
Cell Biochemistry and Biophysics, Vol. 46, No. 3, pp. 193–200
Publisher
Springer Nature
Publication Date
November 2006
DOI
10.1385/cbb:46:3:193
ISSN
1085-9195