Journal article
Interleukin 13 and Serotonin: Linking the Immune and Endocrine Systems in Murine Models of Intestinal Inflammation
Abstract
OBJECTIVE: Infiltration of activated immune cells and increased cytokine production define the immunophenotype of gastrointestinal (GI) inflammation. In addition, intestinal inflammation is accompanied by alteration in the numbers of serotonin (5-hydroxytryptamine; 5-HT) synthesizing enterochromaffin (EC) cells and in 5-HT amount. It has been established that EC cells express interleukin (IL)-13 receptor, additionally IL-13 has been implicated …
Authors
Shajib S; Wang H; Kim JJ; Sunjic I; Ghia J-E; Denou E; Collins M; Denburg JA; Khan WI
Journal
PLOS ONE, Vol. 8, No. 8,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0072774
ISSN
1932-6203