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Studies on the Kinetics of Melatonin and...
Journal article

Studies on the Kinetics of Melatonin and N‐Acetylserotonin in the Rat at Mid‐Light and Mid‐Dark

Abstract

The distribution and disappearance of melatonin and N-acetylserotonin after intravenous injection were studied at mid-light and mid-dark. Male rats were adapted under a photoperiod of 12 h light and 12 h dark cycle for a minimum of 1 week. After the intravenous injection of melatonin (10 micrograms), N-acetylserotonin (10 micrograms), or 3H-melatonin (76 ng), blood samples were collected at 1, 3, 5, 10, 20, 30, 45, 60, 75, 90, and 120 min. The …

Authors

Chan M; Pang SF; Tang PL; Brown GM

Journal

Journal of Pineal Research, Vol. 1, No. 3, pp. 227–236

Publisher

Wiley

Publication Date

July 1984

DOI

10.1111/j.1600-079x.1984.tb00214.x

ISSN

0742-3098