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Effects of chronic blockade of angiotensin II...
Journal article

Effects of chronic blockade of angiotensin II receptor on the maintenance of hypertension and vascular changes in spontaneously hypertensive rats

Abstract

Previous studies have shown that chronic treatment of spontaneously hypertensive rats (SHR) with angiotensin converting enzyme inhibitors is effective in causing the regression of hypertension and vascular structural changes in adult SHR. The purpose of this study was to determine the involvement of angiotensin type 1 receptors in the maintenance of hypertension and vascular changes in adult SHR. Three groups of 15-week-old male SHR were …

Authors

Gillies LK; Lee RM

Journal

Canadian Journal of Physiology and Pharmacology, Vol. 74, No. 9, pp. 1061–1069

Publisher

Canadian Science Publishing

Publication Date

September 1, 1996

DOI

10.1139/y96-107

ISSN

0008-4212