Journal article
The hypercoagulable state in cancer patients
Abstract
Activation of prothrombin and the subsequent reactions of thrombin with its substrates and its major inhibitors, antithrombin III (AT III) and heparin cofactor II (HC II), likely reflect both intravascular and extravascular coagulation. Several studies have reported increased in vivo coagulation in cancer. Whether the increased thrombin production in malignancy is accompanied by a corresponding increase in thrombin inhibition is unknown. This …
Authors
Falanga A; Ofosu FA; Delaini F; Oldani E; Dewar L; Lui L; Barbui T
Journal
Blood Coagulation & Fibrinolysis, Vol. 5, No. 1, pp. s19–s23
Publisher
Wolters Kluwer
Publication Date
January 1994
DOI
10.1097/00001721-199401000-00004
ISSN
0957-5235