Journal article
Determination of molecular size of alpha-1 and alpha-2 adrenoceptors in rat mesenteric artery by radiation inactivation.
Abstract
Radiation inactivation of alpha-1 and alpha-2 adrenoceptors in the purified plasma membranes of rat mesenteric artery has been performed with high energy electrons at -45 to -55 degrees C. Alpha-1 and alpha-2 adrenoceptor inactivation was monitored with [3H] prazosin and [3H]yohimbine binding, respectively. Internal endogenous and external standards of known molecular weight were used in these studies to determine the molecular size. The …
Authors
Agrawal DK; Grover AK; Daniel EE; Jung CY
Journal
Journal of Pharmacology and Experimental Therapeutics, Vol. 236, No. 3, pp. 748–752
Publisher
Elsevier
Publication Date
March 1986
DOI
10.1016/s0022-3565(25)38957-3
ISSN
0022-3565