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Calcium channels in isolated cells and strips of...
Journal article

Calcium channels in isolated cells and strips of longitudinal muscle of rat myometrium

Abstract

The properties of Ca2+ channels in strips and single muscle cells of longitudinal muscle of estrogen-dominated rat myometrium were studied under the effects of elevation of K+ concentration, the partial channel agonist Bay K 8644, and nitrendipine. In isolated strips in 0.5 mM Ca2+, Bay K 8644 (pD2 = 7.8-8.0) lowered the threshold for and enhanced the contractions in response to an elevation of K+ concentration, including the maximum response …

Authors

Kyozuka M; Crankshaw J; Daniel EE

Journal

Canadian Journal of Physiology and Pharmacology, Vol. 65, No. 9, pp. 1976–1981

Publisher

Canadian Science Publishing

Publication Date

September 1, 1987

DOI

10.1139/y87-307

ISSN

0008-4212