Journal article
Is ribonucleotide reductase the transforming function of herpes simplex virus 2?
Abstract
Transformation of cells by herpes simplex virus 2 (HSV-2) can be induced by the BglII C (0.43–0.58 map units) or N (0.58–0.625) fragments of the viral genome1–3. Sequences partially overlapping both fragments (0.566–0.602) encode two 3′ co-terminal mRNAs4–6; these in turn direct the synthesis of two related polypeptides of molecular weight 140,000 (140K) and 35K (refs 4,7), which may be involved in transformation7. Recently, a …
Authors
Huszar D; Bacchetti S
Journal
Nature, Vol. 302, No. 5903, pp. 76–79
Publisher
Springer Nature
Publication Date
3 1983
DOI
10.1038/302076a0
ISSN
0028-0836