Journal article
Telomeres in the Haemopoietic System
Abstract
The limited life span of most blood cells requires the continuous production of cells, which in adults exceeds 10(12) cells/day. This impressive production of cells (approximately 4 x 10(16) cells over a lifetime) is achieved by the proliferation and differentiation of committed progenitor cells, which themselves are derived from a population of pluripotent stem cells with self-renewal potential. Paradoxically, the large majority of stem cells …
Authors
Lansdorp PM; Poon S; Chavez E; Dragowska V; Zijlmans M; Bryan T; Reddel R; Egholm M; Bacchetti S; Martens U
Journal
Novartis Foundation Symposia, Vol. 211, , pp. 209–226
Publisher
Wiley
Publication Date
1997
DOI
10.1002/9780470515433.ch14
ISSN
1528-2511