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The Lyon hypothesis
Journal article

The Lyon hypothesis

Abstract

A curious imbalance appears to occur in nature—the possession of two X chromosomes by one sex (usually the female) compared with only one X in the other sex. Thus, all genes on the X in the female are present in a double dose when compared with the male. Yet most such genes produce the same effect in both sexes. An intriguing theory to account for this equalization of expression has recently been proposed, and the investigation should enhance …

Authors

Davidson RG

Journal

The Journal of Pediatrics, Vol. 65, No. 5, pp. 765–775

Publisher

Elsevier

Publication Date

November 1964

DOI

10.1016/s0022-3476(64)80163-3

ISSN

0022-3476