Journal article
Lung Development and Susceptibility to Chronic Obstructive Pulmonary Disease
Abstract
Chronic obstructive pulmonary disease with emphysema has been considered to be an accelerated involutional disease of aging smokers. However, because only a proportion ( approximately 15%) of smokers develop chronic obstructive pulmonary disease with emphysema, clearly genetic susceptibility must play a significant part in determining both the age of onset and the rapidity of decline in lung function. In mice, interference with key genes, …
Authors
Warburton D; Gauldie J; Bellusci S; Shi W
Journal
Annals of the American Thoracic Society, Vol. 3, No. 8, pp. 668–672
Publisher
American Thoracic Society
Publication Date
November 1, 2006
DOI
10.1513/pats.200605-122sf
ISSN
2329-6933