Journal article
Asthma Induced by Cold Air and Its Relation to Nonspecific Bronchial Responsiveness to Methacholine1–3
Abstract
We compared bronchial responsiveness to isocapnic hyperventilation of cold dry air at -18 degrees C and 0% humidity with bronchial responsiveness to inhaled methacholine in 24 subjects with current or previous asthma and 2 nonasthmatics. Two inhalation tests with each agent were carried out in random order on 4 consecutive days. The response to cold air was expressed as the respiratory heat exchange required to reduce the FEV1 by 10% (PD10 RHE) …
Authors
O'Byrne PM; Ryan G; Morris M; McCormack D; Jones NL; Morse JLC; Hargreave FE
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 125, No. 3, pp. 281–285
Publication Date
March 1982
DOI
10.1164/arrd.1982.125.3.281
ISSN
1073-449X