Journal article
Fifty:fifty poly (DL glycolic acid-lactic acid) copolymer as a drug delivery system for 5-fluorouracil: a histopathological evaluation.
Abstract
Fifty:fifty poly (DL glycolic acid-lactic acid) copolymer (PGLA) is a potentially useful depot drug delivery system for 5-fluorouracil (5-FU). The purpose of this study was to evaluate the fibroinflammatory reaction induced by this polymer. Polymer discs without 5-FU were inserted subconjunctivally in one eye of each of two guinea pigs and four pigmented rabbits (control group), and discs containing 20% 5-FU were inserted subconjunctivally in …
Authors
Gould L; Trope G; Cheng YL; Heathcote JG; Sheardown H; Rootman D; Liu GS; Menon IA
Journal
Canadian Journal of Ophthalmology, Vol. 29, No. 4, pp. 168–171
Publication Date
8 1994
ISSN
0008-4182