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Inhibition of antigen and mitogen-induced...
Journal article

Inhibition of antigen and mitogen-induced lymphocyte transformation by fetal calf serum

Abstract

Use of fetal calf serum as a serum supplement in whole blood microcultures of human lymphocytes resulted in a significant suppression of in vitro stimulation with herpes simplex virus (type 1) antigen, purified protein derivative, and phytohemagglutinin. If the response to viral antigen is weak in autologous serum it may be completely missed if cultures are carried out in fetal calf serum.

Authors

Araby IIE; Chernesky MA; Dent PB

Journal

Canadian Journal of Microbiology, Vol. 23, No. 10, pp. 1482–1485

Publisher

Canadian Science Publishing

Publication Date

October 1, 1977

DOI

10.1139/m77-217

ISSN

0008-4166