Journal article
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
Abstract
Gerard Schellenberg and colleagues report a genome-wide association study of late-onset Alzheimer's disease (LOAD), as part of the Alzheimer Disease Genetics Consortium. They identify common variants in MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 associated with LOAD.
Authors
Naj AC; Jun G; Beecham GW; Wang L-S; Vardarajan BN; Buros J; Gallins PJ; Buxbaum JD; Jarvik GP; Crane PK
Journal
Nature Genetics, Vol. 43, No. 5, pp. 436–441
Publisher
Springer Nature
Publication Date
May 2011
DOI
10.1038/ng.801
ISSN
1061-4036
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Adaptor Proteins, Signal TransducingAge of OnsetAgedAged, 80 and overAlzheimer DiseaseAntigens, CDAntigens, Differentiation, MyelomonocyticCohort StudiesCytoskeletal ProteinsDatabases, GeneticFemaleGenetic Predisposition to DiseaseGenetic VariationGenome-Wide Association StudyHumansMaleMembrane ProteinsMultigene FamilyPolymorphism, Single NucleotideReceptor, EphA1Sialic Acid Binding Ig-like Lectin 3