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The Role of Aluminum in the Functional Iron...
Journal article

The Role of Aluminum in the Functional Iron Deficiency of Patients Treated With Erythropoietin: Case Report of Clinical Characteristics and Response to Treatment

Abstract

The quantitative variation among patients in their response to erythropoietin can be explained, in part, by factors that can independently cause anemia in patients with end-stage renal disease. Aluminum can blunt the effect of erythropoietin, in part by interfering with iron bioavailability. This inhibitory effect cannot be completely overcome by aggressive ferrotherapy, but can be reversed with aluminum chelation therapy. A patient is …

Authors

Donnelly SM; Smith EKM

Journal

American Journal of Kidney Diseases, Vol. 16, No. 5, pp. 487–490

Publisher

Elsevier

Publication Date

November 1990

DOI

10.1016/s0272-6386(12)80065-5

ISSN

0272-6386