Journal article
Increased platelet, but unaltered fibrinogen, accumulation in experimental thrombi in alloxan-induced diabetic rabbits
Abstract
Platelets from diabetic humans and animals have been found previously to be hypersensitive to agonists, including thrombin, in vitro but it is unclear if this hypersensitivity also occurs in vivo and leads to a greater thrombotic tendency. In the present study, the effect of diabetes was examined on thrombus formation and vessel wall responses which result from continuous intimal injury induced by indwelling aortic catheters in rabbits. …
Authors
Winocour PD; Hatton MWC; Richardson M
Journal
Experimental and Molecular Pathology, Vol. 57, No. 2, pp. 134–144
Publisher
Elsevier
Publication Date
October 1992
DOI
10.1016/0014-4800(92)90005-v
ISSN
0014-4800