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Effect of aspirin and salicylate on...
Journal article

Effect of aspirin and salicylate on platelet-vessel wall interactions in rabbits.

Abstract

We performed studies to examine the mechanism responsible for the antithrombogenic effect of aspirin in experimental animals. We measured the effect of 10 and 100 mg/kg doses of aspirin, salicylate, or a combination of both on the accumulation of radiolabeled platelets onto injured carotid arteries in rabbits. The effects of these agents on thrombogenicity measured as platelet accumulation onto injured carotid arteries, were correlated with the …

Authors

Buchanan MR; Hirsh J

Journal

Arteriosclerosis An Official Journal of the American Heart Association Inc, Vol. 4, No. 4, pp. 403–406

Publisher

Wolters Kluwer

Publication Date

July 1984

DOI

10.1161/01.atv.4.4.403

ISSN

0276-5047