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Apnea and oxygen desaturations in children treated...
Journal article

Apnea and oxygen desaturations in children treated with opioids after adenotonsillectomy for obstructive sleep apnea syndrome: a prospective pilot study.

Abstract

BACKGROUND: Recent case reports have alerted the medical community of fatality in children receiving codeine after tonsillectomy and/or adenoidectomy for obstructive sleep apnea syndrome. OBJECTIVE: The objective of this study was to compare the rates of oxygen desaturation before and after adenotonsillectomy in children with obstructive sleep apnea syndrome (OSAS), and to examine the relationship between cytochrome P450 2D6 (CYP2D6) genotype …

Authors

Khetani JD; Madadi P; Sommer DD; Reddy D; Sistonen J; Ross CJD; Carleton BC; Hayden MR; Koren G

Journal

Pediatric Drugs, Vol. 14, No. 6, pp. 411–415

Publication Date

December 1, 2012

DOI

10.2165/11633570-000000000-00000

ISSN

1174-5878