Journal article
Hypoglycemia: a review of definitions used in clinical trials evaluating antihyperglycemic drugs for diabetes
Abstract
OBJECTIVE: To understand the severity and potential impact of heterogeneity in definitions of hypoglycemia used in diabetes research, we aimed to review the hypoglycemia definitions adopted in randomized controlled trials (RCTs).
METHODS: We reviewed 109 RCTs included in the Canadian Agency for Drugs and Technologies in Health reports for the second- and third-line therapy for the patients with type 2 diabetes (T2D).
Authors
Balijepalli C; Druyts E; Siliman G; Joffres M; Thorlund K; Mills EJ
Journal
Clinical Epidemiology, Vol. 9, No. 0, pp. 291–296
Publisher
Taylor & Francis
Publication Date
May 23, 2017
DOI
10.2147/clep.s129268
ISSN
1179-1349