Journal article
Effect of dexamethasone on antigen-induced high molecular weight glycoconjugate secretion in allergic guinea pigs.
Abstract
The ovalbumin-sensitized guinea pig is commonly used as a small animal model of allergic asthma. This animal model exhibits many of the hallmark characteristics observed in patients afflicted with asthma including nonspecific airway hyperreactivity, airway eosinophilia, early and late phase bronchoconstriction, and plasma extravasation into the airways. In addition, mucous hypersecretion in the airways of asthmatic patients is thought to be …
Authors
Savoie C; Plant M; Zwikker M; van Staden CJ; Boulet L; Chan CC; Rodger IW; Pon DJ
Journal
American Journal of Respiratory Cell and Molecular Biology, Vol. 13, No. 2, pp. 133–143
Publisher
American Thoracic Society
Publication Date
8 1995
DOI
10.1165/ajrcmb.13.2.7626283
ISSN
1044-1549