Journal article
Continuous Flow Contact Lens Delivery of Gentamicin to Rabbit Cornea and Aqueous Humor
Abstract
The Morgan Therapeutic Lens (MTL) was investigated as a continuous corneal perfusion system in New Zealand white rabbits. Gentamicin concentration in the cornea and aqueous humor delivered by the MTL was compared to gentamicin drops (13.6 mg/ml) administered every 15 or 30 minutes. Gentamicin (1 mg/ml) or 5 mg/ml was perfused at 10 ml/hr for up to 4.0 hours. At each time interval of 0.5, 1, 2 and 4 hours, homogenized corneas and aqueous humour …
Authors
Rootman DS; Willoughby RP; Bindlish R; Avaria M; Basu PK; Krajden M
Journal
Journal of Ocular Pharmacology and Therapeutics, Vol. 8, No. 4, pp. 317–323
Publisher
Mary Ann Liebert
Publication Date
January 1992
DOI
10.1089/jop.1992.8.317
ISSN
1080-7683