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AMPK in Health and Disease
Journal article

AMPK in Health and Disease

Abstract

The function and survival of all organisms is dependent on the dynamic control of energy metabolism, when energy demand is matched to energy supply. The AMP-activated protein kinase (AMPK) alphabetagamma heterotrimer has emerged as an important integrator of signals that control energy balance through the regulation of multiple biochemical pathways in all eukaryotes. In this review, we begin with the discovery of the AMPK family and discuss the …

Authors

Steinberg GR; Kemp BE

Journal

Physiological Reviews, Vol. 89, No. 3, pp. 1025–1078

Publisher

American Physiological Society

Publication Date

July 2009

DOI

10.1152/physrev.00011.2008

ISSN

0031-9333