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Human symbionts inject and neutralize...
Journal article

Human symbionts inject and neutralize antibacterial toxins to persist in the gut

Abstract

The human gut microbiome is a dynamic and densely populated microbial community that can provide important benefits to its host. Cooperation and competition for nutrients among its constituents only partially explain community composition and interpersonal variation. Notably, certain human-associated Bacteroidetes--one of two major phyla in the gut--also encode machinery for contact-dependent interbacterial antagonism, but its impact within gut …

Authors

Wexler AG; Bao Y; Whitney JC; Bobay L-M; Xavier JB; Schofield WB; Barry NA; Russell AB; Tran BQ; Goo YA

Journal

Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 13, pp. 3639–3644

Publisher

Proceedings of the National Academy of Sciences

Publication Date

March 29, 2016

DOI

10.1073/pnas.1525637113

ISSN

0027-8424