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Tamoxifen effects on respiratory chain complexes...
Journal article

Tamoxifen effects on respiratory chain complexes and creatine kinase activities in an animal model of mania

Abstract

The present study aimed to investigate the effects of tamoxifen (TMX) on locomotor behavior and on the activities of mitochondrial respiratory chain complexes and creatine kinase (CK) in the brain of rats subjected to an animal model of mania induced by d-amphetamine (D-AMPH)-reversion and prevention protocols. The D-AMPH administration increased locomotor activity in saline-treated rats under prevention and reversion treatment; furthermore, …

Authors

Moretti M; Valvassori SS; Steckert AV; Rochi N; Benedet J; Scaini G; Kapczinski F; Streck EL; Zugno AI; Quevedo J

Journal

Pharmacology Biochemistry and Behavior, Vol. 98, No. 2, pp. 304–310

Publisher

Elsevier

Publication Date

4 2011

DOI

10.1016/j.pbb.2011.01.017

ISSN

0091-3057