Journal article
Preventing the Progression of Intestinal Failure–Associated Liver Disease in Infants Using a Composite Lipid Emulsion: A Pilot Randomized Controlled Trial of SMOFlipid
Abstract
BACKGROUND: To examine whether SMOFlipid prevents progression of intestinal failure-associated liver disease (IFALD) in parenteral nutrition (PN)-dependent infants with early IFALD (conjugated bilirubin 17-50 µmol/L, 1-3 mg/dL).
STUDY DESIGN: Pilot multicenter blinded randomized controlled trial comparing SMOFlipid with Intralipid. Patients received the trial lipid for up to 12 weeks, unless they achieved full enteral tolerance sooner. The …
Authors
Diamond IR; Grant RC; Pencharz PB; de Silva N; Feldman BM; Fitzgerald P; Sigalet D; Dicken B; Turner J; Marchand V
Journal
Journal of Parenteral and Enteral Nutrition, Vol. 41, No. 5, pp. 866–877
Publisher
Wiley
Publication Date
July 2017
DOI
10.1177/0148607115626921
ISSN
0148-6071