Journal article
Lost in translation: animal models and clinical trials in cancer treatment.
Abstract
Due to practical and ethical concerns associated with human experimentation, animal models have been essential in cancer research. However, the average rate of successful translation from animal models to clinical cancer trials is less than 8%. Animal models are limited in their ability to mimic the extremely complex process of human carcinogenesis, physiology and progression. Therefore the safety and efficacy identified in animal studies is …
Authors
Mak IW; Evaniew N; Ghert M
Journal
American Journal of Translational Research, Vol. 6, No. 2, pp. 114–118
ISSN
1943-8141