Journal article
Impact of Microgel Morphology on Functionalized Microgel−Drug Interactions
Abstract
The interactions of a range of water-soluble drugs of different charges and hydrophobicities with carboxylic acid-functionalized poly(N-isopropylacrylamide)-based microgels containing different functional group distributions are investigated to determine the impact of drug properties and microgel morphologies on drug uptake and release. The radial distribution of carboxylic acid functional groups in the microgel and the hydrophobicities of the …
Authors
Hoare T; Pelton R
Journal
Langmuir, Vol. 24, No. 3, pp. 1005–1012
Publisher
American Chemical Society (ACS)
Publication Date
February 1, 2008
DOI
10.1021/la7024507
ISSN
0743-7463