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Journal article

Effects of Temperature and Relative Humidity on the Stability of Paper-Immobilized Antibodies

Abstract

The stability of a paper-immobilized antibody was investigated over a range of temperatures (40-140 °C) and relative humidities (RH, 30-90%) using both unmodified filter paper and the same paper impregnated with polyamide-epichlorohydrin (PAE) as supports. Antibody stability decreased with increasing temperature, as expected, but also decreased with increasing RH. At 40 °C, the half-life was more than 10 days, with little dependence on RH. …

Authors

Wang J; Yiu B; Obermeyer J; Filipe CDM; Brennan JD; Pelton R

Journal

Biomacromolecules, Vol. 13, No. 2, pp. 559–564

Publisher

American Chemical Society (ACS)

Publication Date

February 13, 2012

DOI

10.1021/bm2017405

ISSN

1525-7797