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NMD A receptor involvement in spinal inhibitory...
Journal article

NMD A receptor involvement in spinal inhibitory controls of nociception in the rat

Abstract

Low frequency electrical stimulation of high threshold sensory afferents elicits a prolonged inhibition of nociceptive mechanisms in the lightly anaesthetized rat. The present study was to determine the role of NMDA receptor activation in mediation of this inhibition. The latency of the tail withdrawal from a noxious thermal test stimulus to the tip of the tail was taken as an indication of the excitability of nociceptive pathways. Conditioning …

Authors

Romita VV; Henry JL

Journal

Neuroreport, Vol. 7, No. 11, pp. 1705–1708

Publisher

Wolters Kluwer

Publication Date

July 1996

DOI

10.1097/00001756-199607290-00001

ISSN

0959-4965