Simple and Rapid Colorimetric Biosensors Based on...

Simple and Rapid Colorimetric Biosensors Based on DNA Aptamer and Noncrosslinking Gold Nanoparticle Aggregation

Abstract

The color purple. Upon binding of the target +, negatively charged DNA aptamers (shown in purple) dissociate from a gold nanoparticle surface; this results in nanoparticle aggregation and a color change at a chosen salt concentration.

Authors

Zhao W; Chiuman W; Brook MA; Li Y

Journal

ChemBioChem, Vol. 8, No. 7, pp. 727–731

Publisher

Wiley

Publication Date

May 7, 2007

DOI

10.1002/cbic.200700014

ISSN

1439-4227

Associated Experts

Michael Adrian Brook

Professor Emeritus, Faculty of Science

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Yingfu Li

Professor, Faculty of Health Sciences