Journal article
Pinaverium acts as L-type calcium channel blocker on smooth muscle of colon
Abstract
The effect of pinaverium was electrophysiologically characterized and compared with the established L-type calcium channel blockers diltiazem, D600, and nitrendipine on canine colonic circular smooth muscle. Effects were studied on the electrical activity of the smooth muscle cells, in particular the spontaneously occurring slow wave. In addition, effects were examined on spontaneous contraction patterns and contractile activities generated by …
Authors
Malysz J; Farraway LA; Christen MO; Huizinga JD
Journal
Canadian Journal of Physiology and Pharmacology, Vol. 75, No. 8, pp. 969–975
Publisher
Canadian Science Publishing
Publication Date
August 1, 1997
DOI
10.1139/y97-117
ISSN
0008-4212