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Intramuscular interstitial cells of Cajal...
Journal article

Intramuscular interstitial cells of Cajal associated with mast cells survive nitrergic nerves in achalasia

Abstract

Achalasia is dominated by injury to inhibitory nerves. As intramuscular interstitial cells of Cajal (ICC-IM) are proposed to form functional units with nitrergic nerves, their fate in achalasia may be critically important. We studied the relationship between loss of nitrergic nerves and injury to ICC-IM in patients with achalasia and determined associations between ICC-IM and mast cells (MC), using quantitative immunohistochemistry and electron …

Authors

Zarate N; Wang XY; Tougas G; Anvari M; Birch D; Mearin F; Malagelada J; Huizinga JD

Journal

Neurogastroenterology & Motility, Vol. 18, No. 7, pp. 556–568

Publisher

Wiley

Publication Date

7 2006

DOI

10.1111/j.1365-2982.2006.00788.x

ISSN

1350-1925