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Lactobacillus reuteri enhances excitability of...
Journal article

Lactobacillus reuteri enhances excitability of colonic AH neurons by inhibiting calcium‐dependent potassium channel opening

Abstract

Probiotics are live non-pathogenic commensal organisms that exert therapeutic effects in travellers' diarrhea, irritable bowel syndrome and inflammatory bowel disease. Little is known about mechanisms of action of commensal bacteria on intestinal motility and motility-induced pain. It has been proposed that probiotics affect intestinal nerve function, but direct evidence for this has thus far been lacking. We hypothesized that probiotic effects …

Authors

Kunze WA; Mao Y-K; Wang B; Huizinga JD; Ma X; Forsythe P; Bienenstock J

Journal

Journal of Cellular and Molecular Medicine, Vol. 13, No. 8b, pp. 2261–2270

Publisher

Wiley

Publication Date

August 2, 2009

DOI

10.1111/j.1582-4934.2009.00686.x

ISSN

1582-1838