Journal article
Substance P activates a non‐selective cation channel in murine pacemaker ICC
Abstract
Interstitial cells of Cajal (ICC) associated with Auerbach's plexus in the small intestine, provide pacemaker activity to orchestrate peristalsis and mixing. Despite the close apposition between ICC and enteric nerves, little is known about the neural regulation of pacemaker activity. The present study pursues the hypothesis that substance P can affect pacemaker activity through action on non-selective cation channels. Cell-attached and …
Authors
D’antonio C; Wang B; Mckay C; Huizinga JD
Journal
Neurogastroenterology & Motility, Vol. 21, No. 9, pp. 985–e79
Publisher
Wiley
Publication Date
9 2009
DOI
10.1111/j.1365-2982.2009.01318.x
ISSN
1350-1925