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On the origin of rhythmic calcium transients in...
Journal article

On the origin of rhythmic calcium transients in the ICC-MP of the mouse small intestine

Abstract

Interstitial cells of Cajal associated with the myenteric plexus (ICC-MP) are pacemaker cells of the small intestine, producing the characteristic omnipresent electrical slow waves, which orchestrate peristaltic motor activity and are associated with rhythmic intracellular calcium oscillations. Our objective was to elucidate the origins of the calcium transients. We hypothesized that calcium oscillations in the ICC-MP are primarily regulated by …

Authors

Lowie B-J; Wang X-Y; White EJ; Huizinga JD

Journal

AJP Gastrointestinal and Liver Physiology, Vol. 301, No. 5, pp. g835–g845

Publisher

American Physiological Society

Publication Date

11 2011

DOI

10.1152/ajpgi.00077.2011

ISSN

0193-1857