Journal article
Intestinal microbiota influence the early postnatal development of the enteric nervous system
Abstract
BACKGROUND: Normal gastrointestinal function depends on an intact and coordinated enteric nervous system (ENS). While the ENS is formed during fetal life, plasticity persists in the postnatal period during which the gastrointestinal tract is colonized by bacteria. We tested the hypothesis that colonization of the bowel by intestinal microbiota influences the postnatal development of the ENS.
METHODS: The development of the ENS was studied in …
Authors
Collins J; Borojevic R; Verdu EF; Huizinga JD; Ratcliffe EM
Journal
Neurogastroenterology & Motility, Vol. 26, No. 1, pp. 98–107
Publisher
Wiley
Publication Date
1 2014
DOI
10.1111/nmo.12236
ISSN
1350-1925