Journal article
Cholesterol Metabolism and Suicidality in Smith-Lemli-Opitz Syndrome Carriers
Abstract
OBJECTIVE: The authors examined the relationship between cholesterol metabolism and suicidality in carriers of Smith-Lemli-Opitz syndrome and their families. This population has a partial deficiency in 7-dehydrocholesterol reductase (DHCR7), the enzyme that catalyzes the last step in cholesterol biosynthesis.
METHOD: Suicidal behavior, depression, misuse of alcohol and drugs, and family history of psychopathology, including attempted or …
Authors
Lalovic A; Merkens L; Russell L; Arsenault-Lapierre G; Nowaczyk MJM; Porter FD; Steiner RD; Turecki G
Journal
American Journal of Psychiatry, Vol. 161, No. 11, pp. 2123–2126
Publisher
American Psychiatric Association Publishing
Publication Date
November 1, 2004
DOI
10.1176/appi.ajp.161.11.2123
ISSN
0002-953X