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Effect of Amitriptyline and Escitalopram on...
Journal article

Effect of Amitriptyline and Escitalopram on Functional Dyspepsia: A Multicenter, Randomized Controlled Study

Abstract

BACKGROUND & AIMS: Antidepressants are frequently prescribed to treat functional dyspepsia (FD), a common disorder characterized by upper abdominal symptoms, including discomfort or postprandial fullness. However, there is little evidence of the efficacy of these drugs in patients with FD. We performed a randomized, double-blind, placebo-controlled trial to evaluate the effects of antidepressant therapy on symptoms, gastric emptying (GE), and …

Authors

Talley NJ; Locke GR; Saito YA; Almazar AE; Bouras EP; Howden CW; Lacy BE; DiBaise JK; Prather CM; Abraham BP

Journal

Gastroenterology, Vol. 149, No. 2, pp. 340–349.e2

Publisher

Elsevier

Publication Date

8 2015

DOI

10.1053/j.gastro.2015.04.020

ISSN

0016-5085