Journal article
Higher versus lower blood pressure targets for vasopressor therapy in shock: a multicentre pilot randomized controlled trial
Abstract
PurposeIn shock, hypotension may contribute to inadequate oxygen delivery, organ failure and death. We conducted the Optimal Vasopressor Titration (OVATION) pilot trial to inform the design of a larger trial examining the effect of lower versus higher mean arterial pressure (MAP) targets for vasopressor therapy in shock.MethodsWe randomly assigned critically ill patients who were presumed to suffer from vasodilatory shock regardless of …
Authors
Lamontagne F; Meade MO; Hébert PC; Asfar P; Lauzier F; Seely AJE; Day AG; Mehta S; Muscedere J; Bagshaw SM
Journal
Intensive Care Medicine, Vol. 42, No. 4, pp. 542–550
Publisher
Springer Nature
Publication Date
4 2016
DOI
10.1007/s00134-016-4237-3
ISSN
0342-4642