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Structural & functional consequences of...
Journal article

Structural & functional consequences of chronic psychosocial stress on the microbiome & host

Abstract

INTRODUCTION: Given the lasting impact of psychological distress on behavior, along with the role of the microbiome in neurobehavioral development, we sought to examine the relationship between the microbiota and stress-induced behavioral deficits. METHODS: Male C57BL/6 mice exposed to chronic social defeat were subjected to behavioral analysis and profiling of the intestinal microbiome. Mice were also analyzed for phenotypic and functional …

Authors

Bharwani A; Mian MF; Foster JA; Surette MG; Bienenstock J; Forsythe P

Journal

Psychoneuroendocrinology, Vol. 63, , pp. 217–227

Publisher

Elsevier

Publication Date

January 2016

DOI

10.1016/j.psyneuen.2015.10.001

ISSN

0306-4530