Defining the outcome measures for out-of-hospital trials in acute pulmonary edema.

OBJECTIVE: Comparing studies of the effectiveness of out-of-hospital interventions in acute pulmonary edema (APE) is difficult due to the diversity of outcome measures used in the literature. The objective of this study was to define a set of clinically relevant outcome measures for future out-of-hospital trials in APE. METHODS: A Medline search and hand-search of bibliographies was undertaken to develop a list of APE outcome measures. A survey …