Journal article
A restricted signature of miRNAs distinguishes APL blasts from normal promyelocytes
Abstract
MicroRNAs (miRNAs) are small non-coding RNAs involved in the regulation of critical cell processes such as apoptosis, cell proliferation and differentiation. A small set of miRNAs is differentially expressed in hematopoietic cells and seemingly has an important role in granulopoiesis and lineage differentiation. In this study, we analysed, using a quantitative real-time PCR approach, the expression of 12 granulocytic differentiation signature …
Authors
Careccia S; Mainardi S; Pelosi A; Gurtner A; Diverio D; Riccioni R; Testa U; Pelosi E; Piaggio G; Sacchi A
Journal
Oncogene, Vol. 28, No. 45, pp. 4034–4040
Publisher
Springer Nature
Publication Date
November 12, 2009
DOI
10.1038/onc.2009.255
ISSN
0950-9232