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Thymic Epithelial Tumors phenotype relies on...
Journal article

Thymic Epithelial Tumors phenotype relies on miR-145-5p epigenetic regulation

Abstract

BackgroundThymoma and thymic carcinoma are the most frequent subtypes of thymic epithelial tumors (TETs). A relevant advance in TET management could derive from a deeper molecular characterization of these neoplasms. We previously identified a set of microRNA (miRNAs) differentially expressed in TETs and normal thymic tissues and among the most significantly deregulated we described the down-regulation of miR-145-5p in TET. Here we describe the …

Authors

Bellissimo T; Ganci F; Gallo E; Sacconi A; Tito C; De Angelis L; Pulito C; Masciarelli S; Diso D; Anile M

Journal

Molecular Cancer, Vol. 16, No. 1,

Publisher

Springer Nature

Publication Date

December 2017

DOI

10.1186/s12943-017-0655-2

ISSN

1476-4598