Journal article
Association of Granulomatosis With Polyangiitis (Wegener's) With HLA–DPB1*04 and SEMA6A Gene Variants: Evidence From Genome‐Wide Analysis
Abstract
OBJECTIVE: To identify genetic determinants of granulomatosis with polyangiitis (Wegener's) (GPA).
METHODS: We carried out a genome-wide association study (GWAS) of 492 GPA cases and 1,506 healthy controls (white subjects of European descent), followed by replication analysis of the most strongly associated signals in an independent cohort of 528 GPA cases and 1,228 controls.
Authors
Xie G; Roshandel D; Sherva R; Monach PA; Lu EY; Kung T; Carrington K; Zhang SS; Pulit SL; Ripke S
Journal
Arthritis & Rheumatism, Vol. 65, No. 9, pp. 2457–2468
Publisher
Wiley
Publication Date
9 2013
DOI
10.1002/art.38036
ISSN
0004-3591